---
title: >-
  ISPE 2024 Research: Presentation by Kathleen Hurwitz ScD, Catherine Wiener,
  and Chase Latour
description: >-
  Read the latest news on regulatory-grade real-world evidence: ISPE 2024
  Research: Presentation by Kathleen Hurwitz ScD, Catherine Wiener, and Chase
  Latour.
date: '2024-08-27'
category: News
tags:
  - Cross-cutting
  - ISPE
  - Conference Presentation
  - Care
  - R&D
canonical_url: >-
  https://www.headwaterscience.com/resources/news/cross-cutting/ispe-2024-research-presentation-by-kathleen-hurwitz-scd-catherine-wiener-and-chase-latour/
source: Headwater
license: © 2026 Headwater. All rights reserved.
slug: >-
  ispe-2024-research-presentation-by-kathleen-hurwitz-scd-catherine-wiener-and-chase-latour
id: 6lJGkfP4LS9PeCpPjVJlrs
contentType: article
---

Team members Kathleen Hurwtiz, ScD, Catherine Wiener, and Chase Latour helped author a new Target RWE study presented at ISPE 2024 titled “Comparing causal estimands from a sequential nested trial emulation with a treatment decision design to a conventional single point randomized trial: A simulation study.”

The study investigates the potential biases in sequential nested trial emulations, a study designed for rare disease research. Using a simulation framework, the authors compared the results of sequential nested trial emulation to those of single-point randomized trials. Watch this research presentation for valuable insights on using sequential nested trial emulations, highlighting the importance of careful study design and analysis to ensure accurate results: