---
title: >-
  Designing an implementation science clinical trial to integrate hypertension
  and cardiovascular diseases care into existing HIV services package in
  Botswana (InterCARE).
description: >-
  Explore this publication on real-world evidence: Designing an implementation
  science clinical trial to integrate hypertension and cardiovascular diseases
  care…
date: '2024-01-01'
category: Publications
tags:
  - Botswana Harvard AIDS Institute Partnership
  - HIV
  - Abstract/Manuscript
  - Washington University School of Medicine
  - Care
  - 'No'
  - Health System Partner
  - Harvard T.H. Chan School of Public Health
  - Methods/Pharmacoepi
  - R&D
canonical_url: >-
  https://www.headwaterscience.com/resources/publications/acad-botswana-harvard-aids-institute-partnership/designing-an-implementation-science-clinical-trial-to/
source: Headwater Science
license: © 2026 Headwater Science. All rights reserved.
slug: designing-an-implementation-science-clinical-trial-to
id: HfUzta6s9iARFxsNsvGVn
contentType: article
---

## Challenge

Integrating hypertension and cardiovascular disease care into existing HIV service platforms in Botswana required an implementation science trial design, but no formal protocol had been developed and published for this approach.

## Solution

Target RWE's HIV team and collaborators designed and published the InterCARE implementation science clinical trial protocol to integrate hypertension and CVD care into HIV services in Botswana.

## Impact

Publishing the InterCARE trial protocol establishes a rigorous framework for integrated HIV/NCD care delivery research in Botswana, providing a model for similar integration efforts in other high-HIV-burden African settings.

## Use Cases / Links

HIV/NCD integrated care trial protocol for implementation science research in Botswana, Hypertension and CVD care integration framework for HIV service platforms in sub-Saharan Africa