---
title: >-
  Gating and clean room: Constructs designed to facilitate transparency and
  reduce bias in comparative analyses of real-world data
description: >-
  Explore this publication on real-world evidence: Gating and clean room:
  Constructs designed to facilitate transparency and reduce bias in comparative
  analyses…
date: '2024-01-01'
category: Publications
tags:
  - Abstract/Manuscript
  - R&D
  - Approval & Commercialization
  - Amgen
canonical_url: >-
  https://www.headwaterscience.com/resources/publications/abstract-manuscript/gating-and-clean-room-constructs-designed-to-facilitate/
source: Headwater Science
license: © 2026 Headwater Science. All rights reserved.
slug: gating-and-clean-room-constructs-designed-to-facilitate
id: 7fuSmCPXxUs0fjMUGQXbsE
contentType: article
---

## Challenge

Duplicate pair with Row 1 — the gating and clean room manuscript is the same as or closely related to the staging and clean room paper. See Row 1 for full content.

## Solution

Target RWE researchers published this related analysis of the gating and clean room constructs, extending or refining the staging methodology presented in the earlier staging and clean room paper, with Amgen as a co-author and collaborating institution.

## Use Cases/Links

[Read the publication](https://onlinelibrary.wiley.com/doi/10.1002/pds.5770)