---
title: >-
  In-Hospital Treatment Patterns Among Patients Hospitalized with COVID-19 in
  the United States
description: >-
  Explore this publication on real-world evidence: In-Hospital Treatment
  Patterns Among Patients Hospitalized with COVID-19 in the United States..
date: '2022-01-01'
author: M. Alan Brookhart, PhD, Nuvan Rathnayaka
category: Publications
tags:
  - COVID-19
  - ICPE
  - Care
  - Approval & Commercialization
  - 'Yes'
  - Oral Presentation
  - Methods/Pharmacoepi
canonical_url: >-
  https://www.headwaterscience.com/resources/publications/di-covid-19/in-hospital-treatment-patterns-among-patients-hospitalized/
source: Headwater Science
license: © 2026 Headwater Science. All rights reserved.
slug: in-hospital-treatment-patterns-among-patients-hospitalized
id: 4SrxOPNqZj9iY2cjD41ph3
contentType: article
---

## Challenge

Early in the COVID-19 pandemic, treatment patterns for hospitalized patients evolved rapidly and inconsistently across US hospitals, but a real-world characterization of in-hospital treatment utilization across a large nationally representative hospital network was lacking.

## Solution

Target RWE researchers analyzed hospital chargemaster data to describe in-hospital treatment patterns among COVID-19 patients across US hospitals, including antiviral, corticosteroid, and supportive care utilization over time.

## Impact

Providing one of the earliest real-world characterizations of COVID-19 in-hospital treatment patterns contributed critical evidence to the clinical community's rapidly evolving understanding of COVID-19 management.

## Use Cases / Links

COVID-19 in-hospital treatment pattern characterization for clinical guideline and drug development context, Chargemaster data platform demonstration for time-sensitive clinical evidence needs