University of North Carolina at Chapel HillAlexander BreskinApproval & CommercializationYesOral PresentationR&D
Using Bounds to Compare the Strength of Exchangeability Assumptions for Internal and External Validity.
Using Bounds to Compare the Strength of Exchangeability Assumptions for Internal and External Validity
Challenge
Internal validity and external validity require different exchangeability assumptions, but no framework had been developed for formally comparing the strength of these assumptions to guide design choices.
Solution
Target RWE researchers and UNC collaborators developed and presented a formal framework using bounds to compare the relative strength of exchangeability assumptions for internal versus external validity.