Publications

Advancing Principled Pharmacoepidemiologic Research to Support Regulatory and Healthcare Decision Making: The Era of Real-World Evidence.

Advancing Principled Pharmacoepidemiologic Research to Support Regulatory and Healthcare Decision Making: The Era of Real-World Evidence

ISPE Poster Presentation David Pritchard Approval & Commercialization Yes R&D

Assessing artificial censoring weights for clone censor weighting studies: A simulation-based approach.

Assessing artificial censoring weights for clone censor weighting studies: A simulation-based approach

Publications

Total Publications

2026 · AbbVie

Racial and Ethnic Disparities in Access to Advanced Therapies for Atopic Dermatitis in the United States

2026 · Jazz Pharmaceuticals

Real-world polypharmacy and healthcare resource utilization after early-line treatment with cannabidiol for Lennox-Gastaut syndrome, Dravet syndrome, and tuberous sclerosis complex

2026 · Jazz Pharmaceuticals

Real-World Dose Trajectory Patterns and Impact on Polypharmacy Burden and New Antiseizure Medication (ASM) Prescriptions in Patients With Dravet Syndrome (DS), Lennox-Gastaut Syndrome (LGS), or Tuberous Sclerosis Complex (TSC) Receiving Cannabidiol (CBD)

2025 · GSK

Advancing Principled Pharmacoepidemiologic Research to Support Regulatory and Healthcare Decision Making: The Era of Real-World Evidence.

2025 · ISPE

Assessing artificial censoring weights for clone censor weighting studies: A simulation-based approach.

2025 · Poster Presentation

Patterns of Remdesivir Initiation in Immunocompromised Patients Hospitalized With COVID-19

2025 · Jazz Pharmaceuticals

Effect of Cannabidiol on Antiseizure Medication Cycling, Polypharmacy, and Healthcare Resource Utilisation in Patients With Dravet Syndrome, Lennox-Gastaut Syndrome, or Tuberous Sclerosis Complex: Real-World Data from a US Claims Analysis

2024 · M Alan Brookhart

Propensity Score Methods for Confounding Control in Observational Studies of Therapeutics for COVID-19 Infection.

2024 · David Pritchard

Making the Case for Negative Control Outcome Studies in a Real-World Evidence Setting.

2024 · Nuvan Rathnayaka

Seeing Eye to Eye: Enhancing Inter-Team Communication for Reproducible Real-World Evidence.

2024 · Kathleen Hurwitz

Comparing causal estimands from a sequential nested trial emulation with a treatment decision design to a conventional single point randomized trial: A simulation study.

2024 · Poster Presentation

Utilizing Patient Electronic Medical Records to Transform Clinical Trials.

2024 · David A. Pritchard

Prediction in claims databases for epidemiological research.

2023 · M Alan Brookhart

Pragmatic considerations for negative control outcome studies to guide non-randomized comparative analyses: A narrative review.

2023 · Brookhart MA

Controlling for Differential Regression-To-The-Mean via Propensity Scores: A Simulation Study.

2023 · Kathleen Hurwitz

Methods and New Approaches in Pragmatic Trials.

2023 · ICPE

Characterizing the Distribution of Multiple Negative Control Outcome Risk Differences.

2023 · Catherine Weiner

An Analytic Method to Weight Longitudinal Treatment Patterns for Visualization with Sankey Diagrams.

2023 · Botswana Harvard AIDS Institute Partnership

Methods and New Approaches in Pragmatic Trials Case Study: Botswana Combination Prevention Project

2022 · M Alan Brookhart

Lipid Testing Trends Before and After Hospitalization for Myocardial Infarction Among Adults in the United States, 2008-2019.

2022 · University of North Carolina at Chapel Hill

DAG With Omitted Objects Displayed (DAGWOOD): a framework for revealing causal assumptions in DAGs.

2022 · M Alan Brookhart

In-Hospital Treatment Patterns Among Patients Hospitalized with COVID-19 in the United States.

2022 · M Alan Brookhart

Discharged Where? The Importance of Understanding Discharge Dispositions When Estimating In-Hospital Mortality.

2022 · M Alan Brookhart

Fracture Risk Estimation in Post-menopausal Women: A Comparison of Machine Learning Methods and Software Systems.

2022 · M Alan Brookhart

Risk Factors for Mortality and Intensive Care Requirements Among Pediatric Patients Hospitalized with COVID-19 in the United States.

2022 · M Alan Brookhart

The Effect of Remdesivir for The Treatment of COVID-19 on Mortality Among Hospitalized Patients.

2022 · ICPE

One Design to Rule Them All: The Clone-Censor-Weight Design as a General Framework for Epidemiologic Studies.

2022 · M Alan Brookhart

Negative Control Outcomes to Assess the Comparability of Biologics versus Small-molecule Therapeutics for Osteoporosis: Considerations for Differential Non-adherence.

2022 · Andrew G. Allmon

The impact of parametric assumptions on the bias-variance tradeoff for causal analysis of time-to-event outcomes.

2022 · University of North Carolina at Chapel Hill

Fusion Designs for Indirect Treatment Effects.

2022 · Lydia Feinstein

On Teaching Advanced Epidemiologic Methods

2022 · University of North Carolina at Chapel Hill

Bridged treatment comparisons: an illustrative application in HIV treatment.

2022 · Lydia Feinstein

Disparities in Prevalence of Urinary Incontinence among a Nationally Representative Sample of Men, 2005-2016: Findings from the Urologic Diseases in America Project.

2022 · Botswana Harvard AIDS Institute Partnership

Epidemiological and viral characteristics of undiagnosed HIV infections in Botswana

2021 · M Alan Brookhart

Use of negative control outcomes to assess the comparability of patients initiating lipid-lowering therapies.

2021 · ICPE

Use of negative control outcomes to detect mismeasured confounders in administrative data.

2021 · University of California Los Angeles

Fusion designs and estimators for treatment effects.

2020 · M Alan Brookhart

Who are we missing? Underrepresentation of data sources used for pharmacoepidemiology research in the United States.

2020 · ICPE

Real world treatment patterns following the initiation of proprotein convertase subtilisin/kexin type 9 antibody inhibitors among adults in the United States, 2015-2019.

2020 · ICPE

History of lipid lowering therapy use among adults initiating treatment with proprotein convertase subtilisin/kexin type 9 antibody inhibitors in the United States, 2015-2019.

2020 · Sara N. Levintow

Estimating the Effect of Depression on HIV Transmission Risk Behaviors Among People Who Inject Drugs in Vietnam: A Causal Approach.

2020 · University of North Carolina at Chapel Hill

G-computation for policy-relevant effects of interventions on time-to-event outcomes.

2019 · M Alan Brookhart

Using Instrumental Variables to Address Bias from Unobserved Confounders.

2019 · University of North Carolina at Chapel Hill

Commentary: Compositional data call for complex interventions.

2019 · University of North Carolina at Chapel Hill

Using Bounds to Compare the Strength of Exchangeability Assumptions for Internal and External Validity.

2019 · M Alan Brookhart

Informative censoring by health plan disenrollment among commercially insured adults.

2019 · M Alan Brookhart

Nonparametric Bounds for the Risk Function.

2018 · ICPE

Performance of machine learning algorithms for hysterectomy risk prediction among women with endometriosis in the United States.

2018 · University of North Carolina at Chapel Hill

Agreement between electronic health records and administrative claims data for patients with multiple myeloma.

2018 · Breskin, Alexander

A Practical Example Demonstrating the Utility of Single-world Intervention Graphs.

2018 · University of North Carolina at Chapel Hill

Using Negative Control Outcomes to Assess the Comparability of Osteoporosis Treatment Groups.

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