M Alan BrookhartUniversity of North Carolina at Chapel HillAbstract/ManuscriptApproval & CommercializationYesR&D
Who are we missing? Underrepresentation of data sources used for pharmacoepidemiology research in the United States.
Who are we missing? Underrepresentation of data sources used for pharmacoepidemiology research in the United States
Challenge
The representativeness of US data sources used for pharmacoepidemiology research had not been systematically quantified across race, ethnicity, geography, insurance type, and socioeconomic status, leaving unknown the degree to which RWE findings generalize to the broader US population.
Solution
Target RWE researchers systematically characterized the demographic and socioeconomic profiles of populations covered by commonly used US pharmacoepidemiology data sources compared to the US Census, revealing patterns of underrepresentation.