Assessing artificial censoring weights for clone censor weighting studies: A simulation-based approach.

Assessing artificial censoring weights for clone censor weighting studies: A simulation-based approach

Challenge

Clone-censor-weight studies require estimation of artificial censoring weights, but no simulation-based framework existed for evaluating the performance of different censoring weight estimation approaches.

Solution

Target RWE biostatisticians developed a simulation framework to assess artificial censoring weight estimation methods for CCW studies, demonstrating that Cox proportional hazards-based estimation substantially outperforms logistic regression.

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