Lipid Testing Trends Before and After Hospitalization for Myocardial Infarction Among Adults in the United States, 2008-2019

Authors: M. Alan Brookhart, PhDCatherine Wiener

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Challenge

Following hospitalization for myocardial infarction, guideline-recommended lipid testing is critical to secondary prevention management, but the real-world prevalence and trends in post-MI lipid testing in US commercially insured adults had not been characterized at scale.

Solution

Target RWE researchers analyzed lipid testing trends before and after hospitalization for MI using large US administrative claims data, quantifying guideline-concordant testing rates and identifying patient characteristics associated with testing gaps.

Impact

Demonstrating that post-MI lipid testing falls substantially short of guideline recommendations provides real-world evidence of secondary prevention care gaps, supporting pharma partners developing lipid-lowering therapies and informing quality improvement initiatives.