Preexposure prophylaxis uptake, adherence, and persistence during periconception periods among women in South Africa.

PrEP uptake, adherence, and persistence among South African women during the periconception period had been studied cross-sectionally but longitudinal patterns across conception attempts had not been characterized.

Target RWE's HIV team and collaborators analyzed longitudinal PrEP use data among periconception South African women, characterizing uptake, objective adherence trajectories, and persistence patterns across conception attempts.

Providing longitudinal PrEP adherence evidence for periconception South African women informs the design of adherence-enhancing interventions tailored to the specific demands of conception planning.

Longitudinal periconception PrEP adherence characterization for HIV prevention program design, Objective PrEP persistence evidence supporting adherence intervention development for South African women