Commentary: Compositional data call for complex interventions

Author: Alexander Breskin

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Challenge

Compositional data—where components sum to a constant—violate standard regression assumptions, and standard analytic approaches applied to this data type can yield misleading causal estimates about the effects of behavioral interventions.

Solution

Target RWE researchers contributed a commentary in IJE highlighting the methodological challenges of compositional data in epidemiology and the need for methods that appropriately handle the constrained nature of such data when estimating intervention effects.

Impact

Contributing methodological commentary to a leading epidemiology journal demonstrates Target RWE's breadth of methodological expertise and positions the company as a versatile analytic partner for public health and behavioral intervention research.