Challenge

Oral PrEP use patterns among South African women with pregnancy plans—particularly uptake rates and adherence profiles specific to this population—had not been characterized in real-world cohort data.

Solution

Target RWE's HIV team and collaborators analyzed oral PrEP use data among South African women with plans for pregnancy, describing uptake, continuation, and objective adherence patterns during periconception.

Impact

Characterizing oral PrEP use patterns in periconception South African women provides HIV prevention program designers with real-world evidence on uptake barriers and adherence challenges.